左光宏

• 1980年生，湖南常德人
• 理学博士，副教授，博士导师
• 办公室:   复旦大学邯郸校区逸夫科技楼703室
• Email: ghzuo at fudan.edu.cn

教育及工作经历

• 2013 - 至今 复旦大学物理系及理论生命研究中心，讲师、副教授
• 2010 - 2013 上海应用物理研究所，助理研究员
• 2007 - 2010 复旦大学物理系，博士研究生，导师：郝柏林教授、方海平教授
• 2002 - 2005 南京大学物理系，硕士研究生，导师：王炜教授
• 1998 - 2002 湘潭大学物理系，本科

主要研究方向为：

• 蛋白质与纳米颗粒相互作用的理论研究
• 生物进化与分类的CVTree方法的研究
• 生物大分子构象转变的理论研究

代表论著：

1. G.H Zuo, H.L. Hao, J.T. Staley Geographic divergence of “Sulfolobus islandicus” strains assessed by genomic analyses including electronic DNA hybridization confirms they are geovars. Antonie van Leeuwenhoek 105 431-435 (2014)
2. G.H. Zuo, S.G. Kang, P. Xiu, Y.L. Zhao, and R.H. Zhou, Interactions between proteins and carbon nanotubes: exploring origin of nanotoxicology at molecular level. Small 9 1546-1556 (2013)
3. G.H. Zuo, Z. Xu, B.L. Hao, Shigella Strains Are Not Clones of Escherichia coli but Sister Species in the Genus Escherichia. Genomics Proteomics Bioinformatics 11 61-65 (2013)
4. B.Y. Shi, G.H. Zuo, P. Xiu, and R.H. Zhou Binding Preference of Carbon Nanotube Over Proline-Rich Motif Ligand on SH3-Domain: A Comparison with Different Force Fields J. Phys. Chem. B 117 3541-3547 (2013)
5. M. Zhang, G.H. Zuo, J.X. Chen, Y. Gao, and H.P. Fang Aggregated Gas Molecules: Toxic to Protein? Sci. Rep. 3 1660 (2013)
6. G.H. Zuo, P. Xiu, X. Zhou, R.H. Zhou, and H.P. Fang, Protein conformational changes upon binding with carbon nanotubes. Curr. Phys. Chem. 2 12-22 (2012)
7. G.H. Zuo, X. Zhou, Q. Huang, H.P. Fang, and R.H. Zhou, Adsorption of villin headpiece onto graphene, carbon nanotube, and C60: Effect of contacting surface curvatures on binding affinity. J. Phys. Chem. C 115 23323–23328 (2011)
8. G.H. Zuo, W. Gu, H.P. Fang, and R.H. Zhou, Carbon nanotube wins the competitive binding over proline-rich motif ligand on SH3 domain. J. Phys. Chem. C 115 12322-12328 (2011)
9. G.H. Zuo, H.P. Fang, and R.H. Zhou, Nanotoxicity: Exploring the interactions between carbon nanotubes and proteins, Editor J. M. Marulanda, Carbon Nanotubes, InTech Publisher, ISBN 978-953-307-566-2, p539-564, August 2011
10. 左光宏，分子动力学模拟方法研究蛋白质与纳米颗粒的相互作用 科研信息化技术与应用 2 63-71 (2011)
11. G.H. Zuo, Q. Huang, G.H. Wei, R.H. Zhou and H.P. Fang, Plugging into proteins: poisoning protein function by a hydrophobic nanoparticle ACS Nano 4 7508-7514 (2010)
12. G.H. Zuo, Z. Xu, H.J. Yu, B.L. Hao, Jackknife and bootstrap tests of the composition vector trees. Genomics Proteomics Bioinformatics 8 262-267 (2010)
13. G.H. Zuo, W.F. Li, J. Zhang, J. Wang and W. Wang, Folding of a Small RNA Hairpin based on Simulation with Replica Exchange Molecular Dynamics. J. Phys. Chem. B 114 5835-5839 (2010)
14. G.H. Zuo, J. Wang, M. Qin, B. Xue and W. Wang, The effect of solvation-related interaction on the low-temperature dynamics of protein Phys. Rev. E 81 031917 (2010)
15. G.H. Zuo, J. Hu and H.P. Fang, The Effect of the Ordered Water on Protein Folding: An Off-Lattice Go-Like Model Study Phys. Rev. E 79 031925 (2009) (Highlighted by “Nature China”)
16. J. Zhang, W.F. Li, J. Wang, M. Qin, L. Wu, Z.Q. Yan, W.X. Xu, G.H. Zuo and W. Wang, Protein Folding Simulations: From Coarse-Grained Model to All-Atom Model IUBMB Life 61 627-643 (2009)
17. C.L. Wang, H.J. Lu, Z.G. Wang, P. Xiu, B. Zhou, G.H. Zuo, R.Z. Wan, J. Hu and H.P. Fang, Stable Liquid Water Droplet on a Water Monolayer Formed at Room Temperature on Ionic Model Substrates Phys. Rev. Lett. 103 137801 (2009)
18. 23. G.H Zuo, J. Hu and H.P. Fang, Protein folding under the mediation of the ordering water: an off-lattice Go-like model study Chin. Phys. Lett. 24 2426-2429 (2007)
19. G.H. Zuo, J. Wang and W. Wang, Folding with downhill behavior and low cooperativity of proteins. Proteins. 65 165-173 (2006)
20. G.H. Zuo, J. Zhang, J.Wang and W.Wang, Folding behaviour of protein BBL and E3BD with Go-like model. Chin. Phys. Lett. 22 1809-1812 (2005)